abstract：:This study investigated the diurnal output of saliva cortisol in women with symptoms of depression postnatally. Twenty-one depressed and 30 non-depressed women at 7.5 weeks postpartum, and 21 non-perinatal controls, collected saliva at waking, 30 min, and 3 and 12h postwaking. Women who were not depressed postnatally ...

journal_title：Psychoneuroendocrinology

authors： Taylor A,Glover V,Marks M,Kammerer M

更新日期：2009-09-01 00:00:00

abstract：:In addition to abnormalities in social and communication development, a 'need for sameness' and 'resistance to change' are features of autistic spectrum disorders first identified by Kanner in 1943. Our ability to react to change is modulated by the hypothalamic-pituitary-adrenal (HPA) axis, a feature of which is a dr...

journal_title：Psychoneuroendocrinology

authors： Brosnan M,Turner-Cobb J,Munro-Naan Z,Jessop D

更新日期：2009-08-01 00:00:00

abstract：:Attention-deficit/hyperactivity disorder (ADHD) is one of the most common child psychiatric disorders. Previous studies have reported a blunted cortisol response to challenging situations and a decreased cortisol awakening response (CAR) in children with ADHD. As ADHD often is comorbid with oppositional defiant disord...

journal_title：Psychoneuroendocrinology

authors： Freitag CM,Hänig S,Palmason H,Meyer J,Wüst S,Seitz C

更新日期：2009-08-01 00:00:00

abstract：:Dysregulation of hypothalamic-pituitary-adrenal (HPA) axis activity is thought to be an important factor in pathogenesis of depression. In animals, stress or glucocorticoids given in prenatal period lead to long-lasting behavioral and neuroendocrine changes similar to those observed in depressed patients. However, mol...

journal_title：Psychoneuroendocrinology

authors： Szymańska M,Budziszewska B,Jaworska-Feil L,Basta-Kaim A,Kubera M,Leśkiewicz M,Regulska M,Lasoń W

更新日期：2009-07-01 00:00:00

abstract：:In humans, oxytocin nasal administration reduces social-threat perception and improves processes involved in communication and the encoding of positive social cues. The aim of this study was to determine whether oxytocin given as an adjunct to exposure therapy improves treatment for social anxiety disorder (SAD) as in...

journal_title：Psychoneuroendocrinology

authors： Guastella AJ,Howard AL,Dadds MR,Mitchell P,Carson DS

更新日期：2009-07-01 00:00:00

abstract：:Decline in the ovarian steroid, estradiol (E(2)), with the menopause transition may influence cognitive and affective processing of older women and there is evidence that hormone replacement therapies (HRTs) with E(2)-mimetics may provide benefit in some, but not all, women. The parameters that play a role in determin...

journal_title：Psychoneuroendocrinology

authors： Walf AA,Paris JJ,Frye CA

更新日期：2009-07-01 00:00:00

abstract：:Allergic rhinitis (AR) is the fifth most common chronic disease, and the association between allergic disorders and anxiety is well-documented. To investigate how anxiety and stressors modulate skin prick test (SPT) responses and associated inflammatory responses, 28 men and women with AR were selected by clinical his...

journal_title：Psychoneuroendocrinology

authors： Kiecolt-Glaser JK,Heffner KL,Glaser R,Malarkey WB,Porter K,Atkinson C,Laskowski B,Lemeshow S,Marshall GD

更新日期：2009-06-01 00:00:00

abstract：:Hyperactivity of the hypothalamic-pituitary-adrenal axis (HPAA) resulting from fetal programming may play a role in the development of high blood pressure (BP) in black people. We assessed the diurnal salivary cortisol profile in children with and without increased BP and evaluated their mother's HPAA. In a cross-sect...

journal_title：Psychoneuroendocrinology

authors： Boyne MS,Woollard A,Phillips DI,Taylor-Bryan C,Bennett FI,Osmond C,Thomas TY,Wilks RJ,Forrester TE

更新日期：2009-06-01 00:00:00

abstract：:Development of new biomarkers is a constantly evolving field of research endeavor in psychoneuroendocrinology. Salivary biomarkers have received special attention since they are readily accessible and easily obtained. Salivary alpha-amylase (sAA) has been proposed as a sensitive biomarker for stress-related changes in...

journal_title：Psychoneuroendocrinology

authors： Nater UM,Rohleder N

更新日期：2009-05-01 00:00:00

abstract：:This study was designed to explore whether the basal adrenocortical activity is related with pain-related coping, nonverbal pain behavior, depressive mood, and fatigue in patients with acute and chronic nonspecific low back pain. 19 patients with acute low back pain (ALBP) and 24 with chronic low back pain (CLBP) part...

journal_title：Psychoneuroendocrinology

authors： Sudhaus S,Fricke B,Stachon A,Schneider S,Klein H,von Düring M,Hasenbring M

更新日期：2009-05-01 00:00:00

abstract：:Disturbances of volume regulating peptides like vasopressin and atrial natriuretic peptide (ANP) have been described in early abstinent patients. Aim of the present study was to evaluate possible alterations of the promoter-related DNA methylation of the ANP and vasopressin precursor genes and the related mRNA-express...

journal_title：Psychoneuroendocrinology

authors： Hillemacher T,Frieling H,Luber K,Yazici A,Muschler MA,Lenz B,Wilhelm J,Kornhuber J,Bleich S

更新日期：2009-05-01 00:00:00

abstract：:Sex steroids exert important organizational effects on brain structure. Early in life, they are involved in brain sexual differentiation. During puberty, sex steroid levels increase considerably. However, to which extent sex steroid production is involved in structural brain development during human puberty remains un...

journal_title：Psychoneuroendocrinology

authors： Peper JS,Brouwer RM,Schnack HG,van Baal GC,van Leeuwen M,van den Berg SM,Delemarre-Van de Waal HA,Boomsma DI,Kahn RS,Hulshoff Pol HE

更新日期：2009-04-01 00:00:00

abstract：:Epidemiological data suggest that omega-3 polyunsaturated fatty acids (PUFA) consumption may be inversely correlated to the prevalence and severity of depression but little is known about the underlying mechanisms. In this study, we experimentally investigated whether a chronic supplementation with PUFA may induce ant...

journal_title：Psychoneuroendocrinology

authors： Venna VR,Deplanque D,Allet C,Belarbi K,Hamdane M,Bordet R

更新日期：2009-02-01 00:00:00

abstract：:Anorexia nervosa is mostly seen in adolescent females, although the gender-differentiation mechanism is unclear. Corticotropin-releasing factor (CRF), a key peptide for stress responses such as inhibition of food intake, increases in arousal and locomotor activity, and gonadal dysfunction, is thought to be involved in...

journal_title：Psychoneuroendocrinology

authors： Iwasaki-Sekino A,Mano-Otagiri A,Ohata H,Yamauchi N,Shibasaki T

更新日期：2009-02-01 00:00:00

abstract：:Individuals differ widely in cortisol output over the day and cortisol reactivity to challenge, both of which are relevant to disease risk. There is limited evidence concerning the heritability of these differences, so we evaluated the heritability of cortisol levels in the afternoon and cortisol reactivity using a tw...

journal_title：Psychoneuroendocrinology

authors： Steptoe A,van Jaarsveld CHM,Semmler C,Plomin R,Wardle J

更新日期：2009-02-01 00:00:00

abstract：:The second generation antipsychotics clozapine and olanzapine are known to cause weight gain. However, only clozapine is associated with drug-induced fever. Cytokines have been linked to the induction of both weight gain and drug-induced fever. We investigated these potential side effects of clozapine and olanzapine a...

journal_title：Psychoneuroendocrinology

authors： Kluge M,Schuld A,Schacht A,Himmerich H,Dalal MA,Wehmeier PM,Hinze-Selch D,Kraus T,Dittmann RW,Pollmächer T

更新日期：2009-01-01 00:00:00

abstract：:Decline of cognitive function with age may be due, in part, to hormonal changes and it has been hypothesized that higher levels of endogenous sex hormones preserve brain function. The aim of this prospective cohort study was to determine the relative contribution of endogenous sex hormones to cognitive decline in a po...

journal_title：Psychoneuroendocrinology

authors： Muller M,van den Beld AW,Grobbee DE,de Jong FH,Lamberts SW

更新日期：2009-01-01 00:00:00

abstract：:Previous studies have shown that intranasally administered insulin exerts an inhibitory influence on the basal hypothalamic-pituitary-adrenal (HPA) axis activity. To date, however, it remains unclear as to whether intranasal insulin does furthermore affect HPA axis responsiveness in situations of stress. Here, we test...

journal_title：Psychoneuroendocrinology

authors： Bohringer A,Schwabe L,Richter S,Schachinger H

更新日期：2008-11-01 00:00:00

abstract：:Sustained abnormalities of glucocorticoid levels have been associated with neuropsychiatric illnesses such as major depression, posttraumatic stress disorder (PTSD), panic disorder, and obsessive compulsive disorder. The pathophysiological effects of glucocorticoids may depend not only on the amount of glucocorticoid ...

journal_title：Psychoneuroendocrinology

authors： Pekary AE,Sattin A,Blood J,Furst S

更新日期：2008-10-01 00:00:00

abstract：:This study investigated estradiol (E(2)) modulation of the antidepressant effects of a selective serotonin (5-HT) reuptake inhibitor (SSRI; sertraline) and a tricyclic antidepressant (imipramine) as measured by the forced swim test (FST) followed by assessment of gene and protein expression for the 5-HT transporter (S...

journal_title：Psychoneuroendocrinology

authors： Sell SL,Craft RM,Seitz PK,Stutz SJ,Cunningham KA,Thomas ML

更新日期：2008-09-01 00:00:00

abstract：:Exposure of rodents to cats or certain cat odors results in long-term behavioral effects reminiscent of enhanced anxiety that have been considered to model post-traumatic stress disorder. However, other severe stressors such as tail-shock or immobilization in wooden boards (IMO) appear to induce shorter lasting change...

journal_title：Psychoneuroendocrinology

authors： Muñoz-Abellán C,Andero R,Nadal R,Armario A

更新日期：2008-09-01 00:00:00

abstract：:This study examines how gender and menopausal status contribute to age effect on the antidepressant efficacy of repetitive transcranial stimulation (rTMS). Thirty-one women (17 premenopausal, 14 postmenopausal), and 16 men with treatment-refractory bipolar/major depression underwent 10 consecutive sessions of rTMS. Mo...

journal_title：Psychoneuroendocrinology

authors： Huang CC,Wei IH,Chou YH,Su TP

更新日期：2008-07-01 00:00:00

abstract：:Estrogen represents an important factor for the development and function of the nigrostriatal dopamine system. Estrogen also controls sex-specific differentiation and activity of the nigrostriatal dopaminergic system. We used an estrogen receptor-alpha knockout (-/-) model (ERKO) to study the influence of this particu...

journal_title：Psychoneuroendocrinology

authors： Küppers E,Krust A,Chambon P,Beyer C

更新日期：2008-07-01 00:00:00

abstract：:The cold-pressor test (CPT) in which subjects immerse their hand in ice water is among the most commonly used laboratory stressors. While the CPT elicits strong sympathetic nervous system activation, cortisol elevations indicative for the reactivity of the hypothalamus-pituitary-adrenal (HPA) axis are moderate to low ...

journal_title：Psychoneuroendocrinology

authors： Schwabe L,Haddad L,Schachinger H

更新日期：2008-07-01 00:00:00

abstract：:Early life experiences can influence hypothalamus-pituitary-adrenal (HPA) axis regulation in adulthood, in both animals and humans. In humans, they have also been shown to influence adult attachment styles. However, the relationship between adult attachment styles and HPA axis regulation is largely unexplored. The pre...

journal_title：Psychoneuroendocrinology

authors： Quirin M,Pruessner JC,Kuhl J

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Neuroendocrine studies have shown profound alterations in HPA-axis regulation in posttraumatic stress disorder (PTSD). Based on baseline assessments and the response to dexamethasone, a hypothalamic overdrive with enhanced glucocorticoid feedback inhibition has been suggested. The dexamethasone-corticotrophi...

journal_title：Psychoneuroendocrinology

authors： de Kloet C,Vermetten E,Lentjes E,Geuze E,van Pelt J,Manuel R,Heijnen C,Westenberg H

更新日期：2008-04-01 00:00:00

abstract：:Studies of the salivary cortisol awakening response (CAR) may be confounded by delays between waking in the morning and obtaining the 'waking' salivary sample. We used wrist actigraphy to provide objective information about waking time, and studied the influence of delays in taking the waking sample on the CAR. Eighty...

journal_title：Psychoneuroendocrinology

authors： Dockray S,Bhattacharyya MR,Molloy GJ,Steptoe A

更新日期：2008-01-01 00:00:00

abstract：:Frequent or chronic stress as a result of repeated or persistent exposure to social challenges has been shown to affect the glucocorticoid (GC) responsiveness of immune cells in mice. Lipopolysaccharide-stimulated splenocytes of mice that were repeatedly subjected to social disruption were less sensitive to the anti-i...

journal_title：Psychoneuroendocrinology

authors： Engler H,Bailey MT,Engler A,Stiner-Jones LM,Quan N,Sheridan JF

更新日期：2008-01-01 00:00:00

abstract：:Depression is characterized by hypothalamo-pituitary-adrenocortical (HPA) axis hyperactivity. In this major mood disorder, neurosteroids and neurotrophins, particularly brain-derived neurotrophic factor (BDNF), seem to be implicated and have some antidepressant effects. BDNF is highly involved in regulation of the HPA...

journal_title：Psychoneuroendocrinology

authors： Naert G,Maurice T,Tapia-Arancibia L,Givalois L

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:The mechanisms underlying the interaction of psychological stress with the disease course in inflammatory bowel diseases remain unclear. We analyzed the neuroendocrine and cellular immune responses to public speaking stress, and the in vitro adrenergic and glucocorticoid modulation of cytokine production by ...

journal_title：Psychoneuroendocrinology

authors： Langhorst J,Cobelens PM,Kavelaars A,Heijnen CJ,Benson S,Rifaie N,Dobos GJ,Schedlowski M,Elsenbruch S

更新日期：2007-09-01 00:00:00

abstract：:A decline in cognitive function has been reported in type 1 diabetes, but its relation to different disease factors such as hypoglycemic events and peripheral neuropathy is controversial. The objective of the present study was to identify factors that are important for cognitive impairment in type 1 diabetes. A cross-...

journal_title：Psychoneuroendocrinology

authors： Brismar T,Maurex L,Cooray G,Juntti-Berggren L,Lindström P,Ekberg K,Adner N,Andersson S

更新日期：2007-09-01 00:00:00

abstract：:The purpose of this study was to examine the effects of maternal depression and anxiety on the cortisol awakening response (CAR), a marker of the hypothalamic-pituitary-adrenal (HPA) axis function, during pregnancy. Sixty-six pregnant women were studied between 25 and 33 weeks of gestation and were identified as eithe...

journal_title：Psychoneuroendocrinology

authors： Shea AK,Streiner DL,Fleming A,Kamath MV,Broad K,Steiner M

更新日期：2007-09-01 00:00:00

abstract：:Epidemiological and experimental studies have demonstrated that perinatal alterations such as maternal undernutrition are frequently associated with the onset of several chronic adult diseases. Although the physiological mechanisms involved in this "fetal programming" remain largely unknown, it has been shown that ear...

journal_title：Psychoneuroendocrinology

authors： Vieau D,Sebaai N,Léonhardt M,Dutriez-Casteloot I,Molendi-Coste O,Laborie C,Breton C,Deloof S,Lesage J

更新日期：2007-08-01 00:00:00

abstract：:Swim stress regulates forebrain 5-hydroxytryptamine (5-HT) release in a complex manner and its effects are initiated in the serotonergic dorsal raphe nucleus (DRN). The purpose of this study was to examine the effects of swim stress on the physiology of DRN neurons in conjunction with 5-HT immunohistochemistry. Basic ...

journal_title：Psychoneuroendocrinology

authors： Kirby LG,Pan YZ,Freeman-Daniels E,Rani S,Nunan JD,Akanwa A,Beck SG

更新日期：2007-07-01 00:00:00

abstract：:Antidepressants such as SSRIs or mirtazapine have been demonstrated to increase the concentrations of 3alpha-reduced neuroactive steroids throughout several weeks of treatment. However, no data are available on the impact of mood stabilizers such as lithium or carbamazepine on neuroactive steroid levels in depressed p...

journal_title：Psychoneuroendocrinology

authors： Schüle C,Baghai TC,di Michele F,Eser D,Pasini A,Schwarz M,Rupprecht R,Romeo E

更新日期：2007-07-01 00:00:00

abstract：:The prevalence, stability, and impact of blood contamination in children's saliva on the measurement of three of the most commonly assayed hormones were examined. Participants were 363 children (47% boys; ages 6-13 years) from economically disadvantaged families who donated saliva samples on 2 days in the morning, mid...

journal_title：Psychoneuroendocrinology

authors： Granger DA,Cicchetti D,Rogosch FA,Hibel LC,Teisl M,Flores E

更新日期：2007-07-01 00:00:00

abstract：:The impact of lithium on arginine vasopressin (AVP) release has implications for our understanding of the pathophysiology and treatment of mood disorders and for the interpretation of neuroendocrine studies. In this secondary analysis of neuroendocrine, data from 23 patients with chronic major depressive disorder, 41 ...

journal_title：Psychoneuroendocrinology

authors： Watson S,Gallagher P,Smith MS,Young AH,Ferrier IN

更新日期：2007-06-01 00:00:00

abstract：:Elevated physical activity is commonly observed among patients with Anorexia Nervosa (AN) and can manifest in several forms. While elevated physical activity may play a key role in the pathophysiology of this disorder, much remains unknown about it, including the relationship among its various manifestations, and thei...

journal_title：Psychoneuroendocrinology

authors： Klein DA,Mayer LE,Schebendach JE,Walsh BT

更新日期：2007-06-01 00:00:00

abstract：:The hypothalamo-pituitary-adrenal (HPA) axis is hyperactive in major depressive disorder (MDD), and baseline cortisol levels are usually elevated in MDD patients, with alterations of the circadian hormone secretion pattern. The dexamethasone (DEX) suppression test (DST) has been extensively applied to diagnose a dysre...

journal_title：Psychoneuroendocrinology

authors： Steimer T,Python A,Schulz PE,Aubry JM

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:While enhanced cortisol suppression in response to dexamethasone is one of the most consistent biological findings in posttraumatic stress disorder (PTSD), the relative contribution of trauma exposure to this finding remains unclear. METHODS:Assessment of diurnal salivary cortisol levels and 1600 h salivary...

journal_title：Psychoneuroendocrinology

authors： de Kloet CS,Vermetten E,Heijnen CJ,Geuze E,Lentjes EG,Westenberg HG

更新日期：2007-04-01 00:00:00